Glutaredoxin 2 anticorps (Middle Region)

N° du produit ABIN929001

Cet anticorps anti-Glutaredoxin 2 est un anticorps Lapin Polyclonal détectant Glutaredoxin 2 dans WB. Adapté pour Humain.

Aperçu rapide pour Glutaredoxin 2 anticorps (Middle Region) (ABIN929001)

Antigène: Glutaredoxin 2 (GRX2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutaredoxin 2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Glutaredoxin 2 anticorps

Épitope: Middle Region

Purification: Purified

Immunogène: GLRX2 antibody was raised in rabbit using the middle region of GLRX2 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

GLRX2 Blocking Peptide, (ABIN5613785), is also available for use as a blocking control in assays to test for specificity of this GLRX2 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur Glutaredoxin 2

Antigène: Glutaredoxin 2 (GRX2)

Autre désignation: GLRX2

Sujet: GLRX2 is a glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress.GLRX2 is involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress.GLRX2 acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides.GLRX2 can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions.GLRX2 efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Synonyms: Polyclonal GLRX2 antibody, Anti-GLRX2 antibody, glutaredoxin 2 antibody, GRX2 antibody, bA101E13.1 antibody.

Pathways: Cell RedoxHomeostasis